Description

n-(2,4-Difluoro-Phenyl)-Malonamic Acid CAS NO 154935-07-6 is a specialized fluorinated malonamic acid derivative, serving as a critical high-purity building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with specific fluorinated properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and R&D Laboratories: Used in fundamental research exploring new organic reactions and the structure-activity relationships (SAR) of fluorinated compounds.

Basic Information

Item	Detail
Product Name	n-(2,4-Difluoro-Phenyl)-Malonamic Acid
CAS No.	154935-07-6
Molecular Formula	C9H7F2NO3
Molecular Weight	215.15 g/mol
Synonyms	2,4-Difluoro-N-(2,4-difluorophenyl)malonamic acid; Malonamic acid, N-(2,4-difluorophenyl)-; 2-(2,4-Difluoroanilino)-2-oxoacetic acid; (2,4-Difluorophenyl)aminocarbonylacetic acid; 154935-07-6; N-(2,4-Difluorophenyl)malonamic Acid; DFPM Acid
EINECS	Contact for details

Quality Control

Every batch of n-(2,4-Difluoro-Phenyl)-Malonamic Acid is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.