Description

Semparatide CAS NO 154906-40-8 is a synthetic peptide analog of parathyroid hormone (PTH) with significant research and potential therapeutic applications. This compound is of high interest for its role in studying bone metabolism and calcium regulation. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in metabolic and endocrine disorder research. Our supply ensures high purity and batch-to-batch consistency critical for reliable experimental outcomes.

Application

• Pharmaceutical Research & Development: As a key reference standard and active ingredient in preclinical studies for osteoporosis and other bone-related disorders.
• Biochemical Assay Development: Used in the development and validation of in vitro bioassays to study PTH receptor (PTH1R) activation and signaling pathways.
• Metabolic Disorder Studies: A critical tool for investigating the mechanisms of calcium and phosphate homeostasis in animal models.
• Peptide Chemistry & Synthesis: Serves as a complex model compound for advancing peptide synthesis, purification, and analytical techniques.
• Reference Material: Employed as a high-purity calibrant in analytical methods such as HPLC and LC-MS for quality control of related peptide therapeutics.

Basic Information

Item	Detail
Product Name	Semparatide
CAS No.	154906-40-8
Molecular Formula	C₁₈₀H₂₉₁N₅₅O₅₁S₂
Molecular Weight	4101.6 g/mol
Synonyms	RS-66271; LY-333334; Parathyroid Hormone (1-34) amide, human [Tyr34]; hPTH(1-34) amide; Teriparatide acetate; Forteo (brand name reference); Recombinant human parathyroid hormone (1-34) amide
EINECS	Contact for details

Quality Control

Every batch of Semparatide is manufactured and controlled under strict quality management systems. We provide comprehensive analytical data to support its use in research applications, including HPLC purity and mass spectrometry (MS) confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and peptide content. Our quality commitment aligns with the standards expected for pharmaceutical reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.