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Adrenomedullin (Am) (13-52), Human CAS NO 154835-90-2


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CAS No.:154835-90-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Adrenomedullin (Am) (13-52), Human is a specific bioactive peptide fragment derived from the full-length adrenomedullin hormone. This compound is of significant value for research into cardiovascular regulation, endocrine function, and related physiological pathways. It is primarily needed by biotechnology and pharmaceutical R&D sectors, as well as academic institutions, for use as a critical reference standard and investigative tool in biochemical and pharmacological studies.

Application

  • Biomedical Research: Used as a precise molecular tool to study the structure-activity relationship of the adrenomedullin hormone and its receptor interactions.
  • Pharmacology Assays: Serves as a key reference standard in competitive binding assays and activity studies to evaluate potential drug candidates targeting the adrenomedullin system.
  • Cardiovascular Research: Employed in experimental models to investigate the peptide's role in vasodilation, blood pressure regulation, and heart function.
  • Antibody Production & Validation: Acts as an immunogen or a standard for the development and calibration of specific antibodies used in immunoassays like ELISA.
  • Cell Signaling Studies: Utilized to elucidate intracellular signaling pathways activated by adrenomedullin fragments in various cell types.
  • Academic & Institutional Research: Provides a high-purity, well-defined compound for foundational research in physiology and peptide science.

Basic Information

Product Name Adrenomedullin (Am) (13-52), Human
CAS No. 154835-90-2
Molecular Formula C185H301N57O51S2
Molecular Weight 4258.9 g/mol
Synonyms ADM (13-52); Adrenomedullin fragment 13-52; hADM(13-52); Human Adrenomedullin (13-52); Am (13-52); ADM-40; Preproadrenomedullin (153-185) (human); Triptase I; Peptide Fragment of Adrenomedullin
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Quality Control

Our Adrenomedullin (Am) (13-52), Human is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95%
Peptide Content ≥ 80% (by weight)
Amino Acid Composition Conforms to theoretical values
Solubility Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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