Description

Pth (2-38) (Human) is a synthetic peptide fragment corresponding to amino acids 2 through 38 of the human parathyroid hormone. This high-purity biochemical is a critical research tool for studying calcium metabolism, bone physiology, and endocrine signaling pathways. It is essential for pharmaceutical R&D, academic research, and diagnostic assay development targeting metabolic bone disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of PTH receptor binding, signal transduction, and downstream biological effects.
• Drug Discovery & Development: Serves as a key intermediate or reference compound in the development of PTH-based therapeutics for osteoporosis and hypoparathyroidism.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to detect and quantify PTH or related peptides.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the role of specific PTH domains in cellular responses and metabolic regulation.
• Structure-Activity Relationship (SAR) Studies: Utilized to map functional epitopes and understand the contribution of the N-terminal region to PTH bioactivity.

Basic Information

Product Name	Pth (2-38) (Human)
CAS No.	154765-04-5
Molecular Formula	C185H301N55O51S2
Molecular Weight	4133.9 g/mol
Synonyms	Parathyroid Hormone (2-38), human; hPTH (2-38); PTH (2-38) human; Parathyrin (2-38); PTH 2-38 fragment; PTH (2-38) amide; PTH (2-38) (human) trifluoroacetate salt; PTH2-38
EINECS	Contact for details

Quality Control

Our Pth (2-38) (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 70.0%
Amino Acid Composition	Within ±10% of theoretical
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.