Description

Arg-Arg-Arg-Ala-Asp-Asp-Ser-[Asp]5 is a synthetic, high-purity peptide sequence designed for advanced research and development applications. This compound is critical for studying protein-protein interactions, enzyme kinetics, and signal transduction pathways due to its specific arginine-rich and poly-aspartate motif. It is primarily utilized by pharmaceutical R&D teams, academic biochemistry laboratories, and biotechnology companies focused on peptide therapeutics and diagnostic assay development.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, phosphatases, and proteases that recognize arginine or aspartate clusters.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery and optimization of peptide-based drugs targeting cardiovascular and metabolic diseases.
• Cell Biology Studies: Employed to investigate cell-penetrating peptide (CPP) mechanisms and intracellular delivery systems, leveraging its polycationic nature.
• Diagnostic Reagent Formulation: Acts as a critical component in the development of sensitive immunoassays and biosensors for biomarker detection.
• Material Science: Explored for creating bio-inspired materials and coatings due to its ability to interact with various surfaces and ions.

Basic Information

Product Name	Arg-Arg-Arg-Ala-Asp-Asp-Ser-[Asp]5
CAS No.	154444-98-1
Molecular Formula	C58H95N33O30
Molecular Weight	~1690.5 g/mol
Synonyms	R3AD2S(D5) Peptide; H-Arg-Arg-Arg-Ala-Asp-Asp-Ser-Asp-Asp-Asp-Asp-Asp-OH; Polyarginine-Aspartate Sequence; ARAADDS(DDDDD); CPP-Derived Peptide; CAS 154444-98-1; Arg3-Ala-Asp2-Ser-Asp5
EINECS	Contact for details

Quality Control

Every batch of Arg-Arg-Arg-Ala-Asp-Asp-Ser-[Asp]5 is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including multiple orthogonal analytical methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, peptide content, and related substance profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.