Description

2,4(1H,3H)-Pyrimidinedione,5-Fluorodihydro-6-(1-Methylethyl)-,trans-(9Ci) is a fluorinated dihydropyrimidine derivative, a sophisticated heterocyclic compound of significant interest in advanced organic synthesis. Its core value lies in its role as a key chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel antiviral, anticancer, or other therapeutic agents, leveraging its fluorinated pyrimidine scaffold.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy and selectivity.
• Fine Chemical Synthesis: Employed in advanced organic chemistry for constructing complex, chiral molecules due to its defined stereochemistry (trans configuration).
• Biochemical Probe Development: Utilized in medicinal chemistry research to create tool compounds for studying enzyme mechanisms or biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialized organic materials or ligands for catalytic systems.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione,5-Fluorodihydro-6-(1-Methylethyl)-,trans-(9Ci)
CAS No.	154121-09-2
Molecular Formula	C7H11FN2O2
Molecular Weight	174.17 g/mol
Synonyms	trans-5-Fluoro-6-isopropyl-5,6-dihydrouracil; 5-Fluoro-6-(1-methylethyl)-2,4(1H,3H)-pyrimidinedione, trans-; 5-Fluoro-6-isopropyl-5,6-dihydro-2,4(1H,3H)-pyrimidinedione, trans-; 5-Fluoro-6-isopropyl-5,6-dihydropyrimidine-2,4(1H,3H)-dione, trans-; 5-Fluoro-6-(propan-2-yl)-5,6-dihydro-1H-pyrimidine-2,4-dione, trans-; 154121-09-2; trans-5-Fluoro-6-isopropyl-dihydrouracil
EINECS	Contact for details

Quality Control

Our high-purity 2,4(1H,3H)-Pyrimidinedione,5-Fluorodihydro-6-(1-Methylethyl)-,trans-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.