Description

4,6-Dichloro-2-Pyrrolidin-1-Yl-Pyrimidine is a high-value pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring reactive chlorine atoms and a pyrrolidine substituent, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	4,6-Dichloro-2-Pyrrolidin-1-Yl-Pyrimidine
CAS No.	154117-91-6
Molecular Formula	C8H9Cl2N3
Molecular Weight	218.08 g/mol
Synonyms	2,4-Dichloro-6-(pyrrolidin-1-yl)pyrimidine; 2-(Pyrrolidin-1-yl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(1-pyrrolidinyl)pyrimidine; Pyrrolidine, 1-(4,6-dichloro-2-pyrimidinyl)-; 1-(4,6-Dichloropyrimidin-2-yl)pyrrolidine; 154117-91-6; 4,6-Dichloro-2-pyrrolidin-1-ylpyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Pyrrolidin-1-Yl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.