Description

Biotin-Sar-Oh CAS NO 154024-76-7 is a high-purity biotin derivative, specifically a biotinylated amino acid building block. This compound is critical for the synthesis of biotin-conjugated peptides and molecular probes used in advanced biochemical research and diagnostics. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focused on avidin-biotin technology.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for incorporating biotin tags into custom peptide sequences.
• Diagnostic Probe Development: Used to create biotinylated ligands and antibodies for ELISA, lateral flow assays, and other immunoassay platforms.
• Drug Discovery: Enables the preparation of biotin-labeled small molecules or peptides for target identification, pull-down assays, and high-throughput screening.
• Affinity Chromatography: Serves as a precursor for immobilizing biotin onto resins or surfaces to capture streptavidin/avidin-tagged proteins.
• Molecular Imaging: Facilitates the development of biotinylated contrast agents or radioligands for targeted imaging studies.
• Bioconjugation & Linker Chemistry: Provides a reactive handle (OH group) for further functionalization, connecting biotin to various biomolecules or nanoparticles.

Basic Information

Product Name	Biotin-Sar-Oh
CAS No.	154024-76-7
Molecular Formula	C14H25N3O4S
Molecular Weight	331.43 g/mol
Synonyms	Biotin-Sarcosine-OH; Biotinyl-Sar-OH; N-Biotinylsarcosine; (2S)-2-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-methylpentanedioic acid 5-amide; Biotin-AA1-OH (Sar); Biotinylated Sarcosine; Nε-Biotinyl-Nα-methylglycine
EINECS	Contact for details

Quality Control

Our Biotin-Sar-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.