Description

Benzenethiol, 2-Amino-3,5-Difluoro- (9Ci) is a specialized aromatic thiol derivative featuring both amino and fluoro substituents, making it a valuable multi-functional building block for advanced synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds to introduce sulfur, nitrogen, and fluorine atoms into target structures. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and functional materials where its unique reactivity profile enables the creation of novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in transition metal catalysis and organocatalysis due to the presence of both thiol and amino donor groups.
• Material Science: Employed in the synthesis of monomers and functional additives for high-performance polymers, liquid crystals, and electronic materials.
• Chemical Research: A versatile reagent in organic synthesis for constructing complex heterocycles and conducting selective functionalization reactions.

Basic Information

Item	Detail
Product Name	Benzenethiol, 2-Amino-3,5-Difluoro- (9Ci)
CAS No.	153937-30-5
Molecular Formula	C6H5F2NS
Molecular Weight	161.17 g/mol
Synonyms	2-Amino-3,5-difluorobenzenethiol; 3,5-Difluoro-2-aminobenzenethiol; 2-Amino-3,5-difluorothiophenol; 2-Amino-3,5-difluorophenyl mercaptan; 153937-30-5; AI3-40462; SCHEMBL218062; ZINC000257019509
EINECS	Contact for details

Quality Control

Our Benzenethiol, 2-Amino-3,5-Difluoro- (9Ci) is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to maximize shelf-life stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.