Description

3-Cyclopentyloxy-4-Difluoromethoxy-Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoromethoxy and cyclopentyloxy substituents. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where its specific structure enables precise modulation of biological activity and pharmacokinetic properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging the difluoromethoxy group for enhanced biological activity and metabolic stability.
• Organic Synthesis Building Block: Serves as a versatile aldehyde precursor for various condensation, reduction, and cross-coupling reactions in complex molecule assembly.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where the benzaldehyde core and ether linkages contribute to specific material properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in GMP environments.

Basic Information

Item	Details
Product Name	3-Cyclopentyloxy-4-Difluoromethoxy-Benzaldehyde
CAS No.	153587-14-5
Molecular Formula	C₁₃H₁₄F₂O₃
Molecular Weight	256.25 g/mol
Synonyms	4-(Difluoromethoxy)-3-cyclopentyloxybenzaldehyde; 3-Cyclopentyloxy-4-(difluoromethoxy)benzaldehyde; Benzaldehyde, 3-cyclopentyloxy-4-(difluoromethoxy)-; 153587-14-5; 3-Cyclopentyloxy-4-difluoromethoxybenzaldehyde; 4-Difluoromethoxy-3-cyclopentyloxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Cyclopentyloxy-4-Difluoromethoxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.