Description

D-Trp(34) Neuropeptide Y is a synthetic, biologically active peptide analog of the endogenous neurotransmitter Neuropeptide Y (NPY). This modified peptide is of significant interest for its potential to modulate NPY receptor activity, offering a valuable tool for advanced research in neurobiology and metabolic studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies investigating central nervous system disorders, appetite regulation, and cardiovascular function.

Application

• Neuroscience Research: Used as a selective ligand to study the structure-activity relationships (SAR) of NPY receptors (Y1, Y2, Y4, Y5, Y6) and their signaling pathways.
• Pharmacological Studies: Serves as a reference standard or active agent in assays to screen for novel therapeutics targeting obesity, anxiety, and epilepsy.
• Biochemical Tool: Employed in competitive binding assays and receptor autoradiography to characterize receptor distribution and density.
• Metabolic Research: Investigated for its role in energy homeostasis, food intake, and insulin secretion mechanisms.
• Academic & Institutional R&D: A key reagent for universities and research institutes exploring neuropeptide function and drug discovery.
• Peptide Chemistry Development: Used as a model compound in developing novel peptide synthesis, purification, and analytical methodologies.

Basic Information

Product Name	D-Trp(34) Neuropeptide Y
CAS No.	153549-84-9
Molecular Formula	C190H287N55O57S
Molecular Weight	4253.7 g/mol
Synonyms	D-Tryptophan(34)-Neuropeptide Y; [D-Trp34]-NPY; NPY (D-Trp-34); Neuropeptide Y (D-Trp34); [D-Trp34]Neuropeptide Y; D-Trp34-NPY; NPY, D-Trp(34)-; D-Tryptophan-34-NPY
EINECS	Contact for details

Quality Control

Our D-Trp(34) Neuropeptide Y is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade specifications and support reproducible scientific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.