Description

(D-Trp32)-Neuropeptide Y (Human, Rat) CAS NO 153549-78-1 is a synthetic, site-specifically modified analog of the endogenous 36-amino acid neuropeptide Y (NPY). This compound is engineered for enhanced stability and selectivity in research applications, particularly for studying NPY receptor subtype interactions and signaling pathways. It is an essential tool for pharmaceutical R&D, academic research, and biotechnology companies focused on metabolic disorders, cardiovascular function, and central nervous system research.

Application

• Neuroscience Research: A critical tool for investigating the role of Neuropeptide Y in appetite regulation, anxiety, stress response, and circadian rhythms.
• Receptor Pharmacology: Used in binding assays and functional studies to characterize and differentiate between NPY receptor subtypes (Y1, Y2, Y4, Y5, y6).
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics for obesity, diabetes, and cardiovascular diseases.
• Biochemical Assays: Employed in enzyme-linked immunosorbent assays (ELISA), radioimmunoassays (RIA), and other in vitro diagnostic applications.
• Academic & Institutional Research: Fundamental for basic science studies exploring peptide hormone function, G-protein coupled receptor (GPCR) activation, and signal transduction mechanisms.
• Metabolic Disorder Studies: Key reagent in models studying energy homeostasis, food intake, and lipid metabolism.

Basic Information

Product Name	(D-Trp32)-Neuropeptide Y (Human, Rat)
CAS No.	153549-78-1
Molecular Formula	C190H287N55O57S
Molecular Weight	4252.7 g/mol
Synonyms	[D-Tryptophan32]-Neuropeptide Y; NPY (22-36), D-Trp32-; D-Trp32-NPY; Neuropeptide Y (human, rat) (D-Trp32)-; (D-Trp32)-NPY; NPY analog (D-Trp32); TFA salt of (D-Trp32)-Neuropeptide Y; [D-Trp32]NPY
EINECS	Contact for details

Quality Control

Every batch of (D-Trp32)-Neuropeptide Y (Human, Rat) is synthesized under cGMP-like conditions and undergoes rigorous analytical characterization to ensure identity, purity, and biological activity. Our products are supported by comprehensive Certificates of Analysis (COA) detailing results from HPLC, MS, and amino acid analysis. We adhere to stringent quality standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak confirmed
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Confirmed by receptor binding assay (data available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.