Description

H-D-Ala-Gln-Octadecyl Ester Hcl is a synthetic, protected dipeptide derivative designed for advanced research and pharmaceutical development. This compound is a crucial building block in peptide synthesis, offering a lipophilic octadecyl (stearyl) ester group that enhances membrane permeability and stability. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, peptide drug discovery, and the development of novel therapeutic agents and prodrugs.

Application

• Medicinal Chemistry Research: Serves as a key intermediate in the synthesis of novel peptide-based drug candidates and prodrugs.
• Pharmaceutical Development: Used in the design and optimization of therapeutic peptides to improve bioavailability and metabolic stability.
• Bioconjugation & Labeling: Acts as a precursor for creating lipidated peptides for cell-penetration studies and targeted delivery systems.
• Biochemical Research: Employed in studies investigating peptide-lipid interactions, membrane association, and signal transduction pathways.
• Cosmeceutical Applications: Potential use as a bioactive ingredient in advanced skincare formulations targeting peptide-mediated skin repair.

Basic Information

Product Name	H-D-Ala-Gln-Octadecyl Ester Hcl
CAS No.	153508-74-8
Molecular Formula	C26H52N4O5 • HCl
Molecular Weight	545.18 g/mol
Synonyms	H-D-Ala-Gln-Ocde HCl; H-D-Alanyl-L-glutamine Octadecyl Ester Hydrochloride; D-Alanyl-L-glutamine Stearyl Ester Hydrochloride; N-[(3S)-5-Amino-1-[[(2R)-1-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentan-3-yl]octadecanamide Hydrochloride; Stearyl D-Alanyl-L-glutamate Hydrochloride; Protected D-Ala-Gln Ester; Lipopeptide Intermediate 153508-74-8
EINECS	Contact for details

Quality Control

Our H-D-Ala-Gln-Octadecyl Ester Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.