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2-Fluoro-4-Iodo-6-Nitroaniline CAS NO 153505-44-3


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CAS No.:153505-44-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-4-Iodo-6-Nitroaniline is a halogenated and nitrated aniline derivative, a versatile building block in advanced organic synthesis. Its unique molecular structure, featuring fluorine, iodine, and nitro functional groups, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and metabolic stability.
  • Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
  • Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine substituent.
  • Dye and Pigment Intermediate: Employed in the synthesis of complex, halogenated azo dyes and pigments for high-performance applications.
  • Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for creating libraries of compounds for high-throughput screening.

Basic Information

Product Name 2-Fluoro-4-Iodo-6-Nitroaniline
CAS No. 153505-44-3
Molecular Formula C6H4FIN2O2
Molecular Weight 282.01 g/mol
Synonyms 2-Fluoro-4-iodo-6-nitrobenzenamine; 4-Amino-3-fluoro-5-iodonitrobenzene; 6-Nitro-2-fluoro-4-iodoaniline; Benzenamine, 2-fluoro-4-iodo-6-nitro-; 3-Fluoro-5-iodo-2-nitroaniline
EINECS Contact for details

Quality Control

Every batch of 2-Fluoro-4-Iodo-6-Nitroaniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item Specification
Appearance Yellow to orange crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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