Description

2,3-Difluoro-6-Nitroaniline is a high-purity aromatic amine derivative, distinguished by its strategically positioned fluorine and nitro substituents. This compound matters as a critical building block in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast azo dyes and pigments.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aniline derivatives.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and exploring new synthetic pathways involving fluorinated nitroanilines.

Basic Information

Product Name	2,3-Difluoro-6-Nitroaniline
CAS No.	153505-39-6
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	2,3-Difluoro-6-nitrobenzenamine; 6-Nitro-2,3-difluoroaniline; 2,3-Difluoro-6-nitro-phenylamine; Benzenamine, 2,3-difluoro-6-nitro-; 2,3-DFNA; 2,3-Difluoro-6-nitroaniline (DFNA)
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.