Description

3-Amino-2,6-difluoro(trifluoromethoxy)benzene is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and trifluoromethoxy substituents, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This specialty chemical is primarily demanded by the pharmaceutical and agrochemical industries for the research and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other monomers used in high-performance electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing functional groups into polymer backbones, improving chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments with enhanced color fastness and unique optical properties.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination chemistry and creating novel chemical entities for material science.

Basic Information

Product Name	3-Amino-2,6-Difluoro(Trifluoromethoxy)Benzene
CAS No.	153338-24-0
Molecular Formula	C7H4F5NO
Molecular Weight	213.11 g/mol
Synonyms	2,6-Difluoro-3-(trifluoromethoxy)aniline; 3-Amino-2,6-difluorobenzotrifluoromethoxy; 2,6-Difluoro-α,α,α-trifluoro-m-anisidine; 3-(Trifluoromethoxy)-2,6-difluoroaniline; 2,6-Difluoro-3-(trifluoromethoxy)benzenamine; 1-Amino-2,6-difluoro-3-(trifluoromethoxy)benzene; Benzenamine, 2,6-difluoro-3-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 3-Amino-2,6-difluoro(trifluoromethoxy)benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.