Description

Boc-L-Aspartimol T-Butyl Ester is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of complex molecules. It is particularly valuable in the pharmaceutical industry for the synthesis of peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of peptide-based drugs and bioactive compounds.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce aspartic acid residues with orthogonal protecting groups.
• Protease Inhibitor Research: Serves as a scaffold for developing inhibitors targeting aspartyl proteases.
• Bioconjugation Chemistry: Utilized in the preparation of modified peptides for drug delivery systems and diagnostic agents.
• Chemical Biology: Employed in the study of protein-protein interactions and enzyme mechanisms.
• Academic & R&D: A standard reagent in university and industrial research laboratories for methodological development.

Basic Information

Product Name	Boc-L-Aspartimol T-Butyl Ester
CAS No.	153287-86-6
Molecular Formula	C₁₃H₂₄N₂O₅
Molecular Weight	288.34 g/mol
Synonyms	Boc-Aspartimol-OtBu; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid; N-(tert-Butoxycarbonyl)-L-aspartic acid 4-tert-butyl ester; Boc-L-Asp(OtBu)-OH; Boc-Asp(OtBu)-OH; tert-Butyl N-[(1S)-3-(tert-butoxy)-1-carboxy-3-oxopropyl]carbamate; L-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our Boc-L-Aspartimol T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.