Description

H-Val-Val-Phe-Oh is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid of the Val-Val-Phe sequence. This compound serves as a critical building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by R&D scientists and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of longer, more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard, substrate, or inhibitor in enzymatic studies and proteomics research.
• Peptide Library Construction: Essential building block in solid-phase and solution-phase peptide synthesis for creating combinatorial libraries for drug discovery.
• Prodrug Development: Investigated for its potential in designing prodrugs to enhance the bioavailability and pharmacokinetic profiles of peptide therapeutics.
• Cosmeceutical Applications: Explored as a bioactive ingredient in advanced skincare formulations targeting specific biological pathways.

Basic Information

Product Name	H-Val-Val-Phe-Oh
CAS No.	153247-47-3
Molecular Formula	C₂₁H₃₁N₃O₄
Molecular Weight	389.49 g/mol
Synonyms	L-Valyl-L-valyl-L-phenylalanine; Val-Val-Phe; VVF; H-Val-Val-Phe-OH; Tripeptide VVF; N-(N-L-Valyl-L-valyl)-L-phenylalanine; L-Phenylalanine, L-valyl-L-valyl-; UNII-9J3V6S6A1F
EINECS	Contact for details

Quality Control

Our H-Val-Val-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on anhydrous basis)
Optical Rotation	-30° to -40° (c=1 in AcOH)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.