Description

D-3-Thienylalanine is a non-natural, chiral amino acid derivative featuring a thiophene ring, a key structural motif in medicinal chemistry. This compound serves as a critical building block for the synthesis of novel pharmaceuticals and bioactive molecules, enabling the exploration of structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing enzyme inhibitors, peptide mimetics, and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A versatile chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Peptidomimetics: Used to incorporate the thienyl moiety into peptide backbones to enhance metabolic stability and modulate biological activity.
• Enzyme Inhibitor Design: Serves as a core structure or side-chain analog in the design of inhibitors for various enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective synthetic routes.
• Material Science Research: Potential precursor for functionalized organic materials and ligands in catalysis.

Basic Information

Product Name	D-3-Thienylalanine
CAS No.	152612-26-5
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	(R)-2-Amino-3-(thiophen-3-yl)propanoic acid; D-3-(3-Thienyl)alanine; D-β-(3-Thienyl)alanine; (R)-3-(Thiophen-3-yl)alanine; D-3-Thienylalanine; D-3-Thiophenealanine; (R)-2-Amino-3-(3-thienyl)propionic acid; D-3-Thienyl-alanine
EINECS	Contact for details

Quality Control

Our D-3-Thienylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) documenting purity, enantiomeric excess, and related substances is provided with every shipment to support your R&D and cGMP workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% ee (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.