Description

n-Acetyl Polylysine is a chemically modified derivative of the natural polymer poly-L-lysine, where the ε-amino groups are acetylated. This modification significantly alters its physicochemical properties, making it a valuable synthetic polymer for advanced material science and biomedical applications. It is particularly sought after by researchers and manufacturers in the pharmaceutical, cosmetic, and biotechnology sectors. The compound is recognized for its utility in creating biocompatible coatings, drug delivery systems, and as a functional material scaffold.

Application

• Biomedical Research: Used as a model cationic polymer for studying cell-polymer interactions, gene delivery vectors, and tissue engineering scaffolds.
• Drug Delivery Systems: Serves as a functional excipient or coating material for controlled-release formulations and nanoparticle drug carriers.
• Cosmetic Formulations: Employed as a film-forming agent, moisturizer, or conditioning polymer in advanced skincare and haircare products.
• Surface Modification: Applied as a biocompatible coating to modify the surface properties of medical devices, implants, and diagnostic tools.
• Bioconjugation & Immobilization: Acts as a versatile linker or spacer arm for the immobilization of enzymes, antibodies, or other biomolecules on solid supports.
• Material Science: Utilized in the synthesis of hydrogels, smart polymers, and other functional materials with tailored charge and solubility profiles.

Basic Information

Product Name	n-Acetyl Polylysine
CAS No.	152473-69-3
Molecular Formula	(C8H14N2O2)n • xC2H4O2
Molecular Weight	Variable (Polymer)
Synonyms	Poly(Nε-acetyl-L-lysine); Acetylated Poly-L-lysine; Nε-Acetylpolylysine; Poly(acetyllysine); PLL-Ac; Ac-PLL; Polylysine acetate, acetylated; Poly(lysine-co-acetyllysine)
EINECS	Contact for details

Quality Control

Our n-Acetyl Polylysine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistency in molecular weight distribution, degree of acetylation, purity, and performance. Certificates of Analysis (COA) detailing specific results for key parameters are provided with every shipment. We support compliance with cGMP guidelines for pharmaceutical and cosmetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Degree of Acetylation	≥ 95% (or as specified)
Assay (HPLC)	≥ 95.0%
Molecular Weight (Avg.)	1,000 - 50,000 Da (Customizable)
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.