Description

Fmoc-Trp(For)-Oh is a protected derivative of the amino acid tryptophan, specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly when incorporating tryptophan residues. It is an essential building block for the pharmaceutical, biotechnology, and life sciences industries, enabling the production of complex peptides for therapeutic and diagnostic applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the automated synthesis of custom peptides.
• Pharmaceutical Research: Used in the development and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Serves as a reagent for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial R&D: Fundamental reagent for studying protein structure-function relationships and peptide biochemistry.
• Production of Protected Peptide Fragments: For use in fragment condensation strategies to construct long or challenging peptide sequences.

Basic Information

Product Name	Fmoc-Trp(For)-Oh
CAS No.	152338-45-9
Molecular Formula	C₂₉H₂₆N₂O₅
Molecular Weight	482.53 g/mol
Synonyms	Fmoc-N-Formyltryptophan; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-formyl-L-tryptophan; Fmoc-L-Trp(For)-OH; N-α-Fmoc-N-ω-formyl-L-tryptophan; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-3-(1-formylindol-3-yl)propanoic acid; Fmoc-Trp(CHO)-OH; Fmoc-Nin-formyl-L-tryptophan; Nω-Formyl-Nα-Fmoc-L-tryptophan
EINECS	Contact for details

Quality Control

Our Fmoc-Trp(For)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.