Description

Ac-Arg-Phe-Met-Trp-Met-Thr-Nh2 CAS NO 152274-67-4 is a synthetic heptapeptide derivative, acetylated at the N-terminus and amidated at the C-terminus, featuring a sequence rich in methionine and tryptophan residues. This compound is of significant interest in biochemical and pharmaceutical research due to its potential role as a substrate or inhibitor in enzymatic studies and as a key intermediate in the development of novel peptide-based therapeutics. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on neurobiology, metabolic pathways, and advanced drug discovery platforms.

Application

• Biochemical Research: Used as a specialized substrate or reference standard in enzyme kinetics studies, particularly for proteases and peptidases.
• Pharmaceutical R&D: Serves as a critical intermediate or lead compound in the synthesis and screening of novel peptide-based drug candidates.
• Neuroscience Studies: Investigated for potential bioactivity in neurological pathways, given the presence of key amino acids like tryptophan and methionine.
• Proteomics & Peptide Mapping: Employed as a calibration standard or model compound in mass spectrometry and HPLC method development for complex peptide analysis.
• Academic Research: Utilized in university laboratories for teaching and advanced research in peptide chemistry, structure-activity relationships (SAR), and molecular biology.

Basic Information

Product Name	Ac-Arg-Phe-Met-Trp-Met-Thr-Nh2
CAS No.	152274-67-4
Molecular Formula	C52H76N16O10S2
Molecular Weight	1157.4 g/mol
Synonyms	Acetyl-Arg-Phe-Met-Trp-Met-Thr-amide; Ac-Arg-Phe-Met-Trp-Met-Thr-NH2; Ac-RFM(OMe)WM(OMe)T-NH2 (protected form reference); Heptapeptide Ac-R-F-M-W-M-T-NH2; N-Acetyl-L-arginyl-L-phenylalanyl-L-methionyl-L-tryptophyl-L-methionyl-L-threoninamide; Ac-Arg-Phe-Met-Trp-Met-Thr-NH2; Custom Sequence 152274-67-4
EINECS	Contact for details

Quality Control

Every batch of Ac-Arg-Phe-Met-Trp-Met-Thr-Nh2 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive analysis by HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, related substances, and residual solvent levels is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For optimal results, store the product desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.