Description

3-Amino-2-(trifluoromethyl)-4(3H)-quinazolinone is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethylated quinazolinone core, which is a privileged scaffold in medicinal chemistry for modulating the physicochemical and pharmacokinetic properties of drug candidates. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the quinazolinone moiety.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function or protein-protein interactions.
• Material Science Research: Potential building block for advanced organic electronic materials or specialty polymers due to its fused aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorinated heterocycle chemistry.

Basic Information

Product Name	3-Amino-2-(Trifluoromethyl)-4(3H)-Quinazolinone
CAS No.	152062-96-9
Molecular Formula	C9H6F3N3O
Molecular Weight	229.16 g/mol
Synonyms	3-Amino-2-(trifluoromethyl)-3,4-dihydroquinazolin-4-one; 2-(Trifluoromethyl)-3-amino-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-amino-2-(trifluoromethyl)-; 3-Amino-2-trifluoromethylquinazolin-4(3H)-one; ATAQ; 152062-96-9
EINECS	Contact for details

Quality Control

Our production of 3-Amino-2-(trifluoromethyl)-4(3H)-quinazolinone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.