Description

Pro-Gln-Arg-Phe-Amide Trifluoroacetate Salt is a high-purity synthetic peptide derivative, specifically a tetrapeptide amide, supplied as its trifluoroacetate salt for enhanced stability and solubility. This compound serves as a critical building block and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in drug discovery, proteomics, and biochemical studies.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis and study of novel peptide-based therapeutics.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Proteomics & Metabolic Studies: Employed as a model compound for mass spectrometry calibration and in studies of peptide metabolism and signaling pathways.
• Academic Research: Serves as a crucial reagent in university and institutional labs for fundamental research in biochemistry and molecular biology.
• Peptide Library Synthesis: Acts as a building block in the combinatorial synthesis of peptide libraries for high-throughput screening.
• Quality Control & Analytical Standards: Used as a certified reference material (CRM) to validate analytical methods like HPLC and LC-MS in QC laboratories.

Basic Information

Product Name	Pro-Gln-Arg-Phe-Amide Trifluoroacetate Salt
CAS No.	152050-35-6
Molecular Formula	C30H46N10O8 • xC2HF3O2
Molecular Weight	698.77 g/mol (Free base)
Synonyms	L-Prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide Trifluoroacetate; Pro-Gln-Arg-Phe-NH2 TFA Salt; PQRFa-NH2 TFA Salt; Tetrapeptide Amide TFA Salt; 152050-35-6; PGlu-Arg-Phe-NH2 TFA; H-Pro-Gln-Arg-Phe-NH2 • CF3COOH
EINECS	Contact for details

Quality Control

Our Pro-Gln-Arg-Phe-Amide Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade biochemicals. Certificates of Analysis (COA) with detailed HPLC purity, MS confirmation, and residual solvent data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Residual TFA (NMR/Titration)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.