Description

Glutamyl-Glutamyl-Phosphotyrosyl-Alanyl-Alanine is a synthetic peptide sequence containing a phosphorylated tyrosine residue, a key post-translational modification in biological signaling. This compound is a critical biochemical tool for studying protein-protein interactions, kinase activity, and signal transduction pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery, assay development, and as a reference standard.

Application

• Biochemical Research: As a substrate or inhibitor in enzymatic assays to study protein tyrosine kinases (PTKs) and phosphatases (PTPs).
• Drug Discovery: Screening for novel therapeutics targeting phosphotyrosine-mediated signaling pathways in oncology and immunology.
• Diagnostic Development: Used in the development of ELISA and other immunoassays to detect specific antibodies or kinase activity.
• Cell Signaling Studies: Investigating intracellular signal transduction mechanisms involving SH2 and PTB domain interactions.
• Reference Standard: Serves as a high-purity calibrant in analytical methods like HPLC and mass spectrometry for quality control.
• Peptide Synthesis: As a building block or intermediate for the synthesis of longer, more complex phosphopeptides.

Basic Information

Item	Detail
Product Name	Glutamyl-Glutamyl-Phosphotyrosyl-Alanyl-Alanine
CAS No.	151957-35-6
Molecular Formula	C30H41N6O16P
Molecular Weight	772.66 g/mol
Synonyms	Glu-Glu-pTyr-Ala-Ala; EE(pY)AA; Phosphotyrosine-containing Peptide; pY Peptide; H-Glu-Glu-pTyr-Ala-Ala-OH; L-Glutamyl-L-glutamyl-O-phosphono-L-tyrosyl-L-alanyl-L-alanine; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-[4-(phosphonooxy)phenyl]propanoyl]amino]propanoyl]amino]propanoic acid
EINECS	Contact for details

Quality Control

Our Glutamyl-Glutamyl-Phosphotyrosyl-Alanyl-Alanine is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our processes are designed to meet the exacting standards required for biochemical and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep under inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.