Description

L-Leucine Nitrate is a high-purity, specialized amino acid derivative combining the essential branched-chain amino acid L-Leucine with a nitrate counterion. This compound is valued for its role as a stable and bioavailable source of both leucine and nitrate ions, which are critical in various biochemical and industrial processes. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and advanced research sectors for applications requiring precise chemical composition and reliable performance.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and as a building block for more complex nitrogen-containing molecules.
• Nutraceutical & Sports Nutrition: Incorporated into specialized dietary supplements and performance formulas where a combined source of an essential amino acid and nitrate is desired for metabolic support.
• Biochemical Research: Serves as a key reagent or standard in metabolic pathway studies, cell culture media formulation, and enzymatic research.
• Microbiological Media: Acts as a defined nitrogen source in the preparation of selective culture media for industrial fermentation and microbiological assays.
• Cosmetic & Personal Care: Potential use in advanced skincare formulations for its amino acid properties and role in nitrogen delivery systems.

Basic Information

Product Name	L-Leucine Nitrate
CAS No.	151894-40-5
Molecular Formula	C6H13NO2 • HNO3 or C6H14N2O5
Molecular Weight	194.17 g/mol (for C6H14N2O5)
Synonyms	L-Leucine nitrate salt; Leucine nitrate; (S)-2-Amino-4-methylpentanoic acid nitrate; (S)-2-Amino-4-methylvaleric acid nitrate; H-Leu-OH • HNO3; L-2-Amino-4-methylpentanoic acid nitrate; L-α-Aminoisocaproic acid nitrate
EINECS	Contact for details

Quality Control

Our L-Leucine Nitrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We can supply material meeting various pharmacopeial or in-house specifications to suit your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +14.5° to +16.5° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% L-Isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.