Description

Dansyl-Prolyl-Glutaminyl-Arginyl-Phenylalaninamide is a synthetic peptide derivative featuring a dansyl fluorophore, designed for advanced biochemical research and development. This compound is valued for its role as a specialized substrate or probe in enzymatic studies and fluorescence-based assays. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on protease activity, peptide metabolism, and high-throughput screening applications.

Application

• Protease & Enzyme Substrate: Used as a fluorogenic or chromogenic substrate to study the kinetics and specificity of various proteases, including trypsin-like enzymes.
• Biochemical Research: Serves as a critical tool in mechanistic studies of peptide bond cleavage, enzyme inhibition, and signal transduction pathways.
• Diagnostic Development: Employed in the development of fluorescence-based diagnostic assays and kits for detecting enzymatic activity in clinical or research samples.
• Pharmaceutical Screening: Acts as a key component in high-throughput screening (HTS) platforms to identify and characterize new therapeutic enzyme inhibitors.
• Peptide Chemistry Studies: Utilized as a model compound in studies of peptide stability, modification, and fluorescence labeling techniques.

Basic Information

Product Name	Dansyl-Prolyl-Glutaminyl-Arginyl-Phenylalaninamide
CAS No.	151870-87-0
Molecular Formula	C₄₀H₅₈N₁₂O₉S
Molecular Weight	883.04 g/mol
Synonyms	Dansyl-Pro-Gln-Arg-Phe-NH₂; Dns-Pro-Gln-Arg-Phe-NH₂; 5-(Dimethylamino)naphthalene-1-sulfonyl-Pro-Gln-Arg-Phe-amide; Dansyl Peptide Substrate; Fluorogenic Peptide Substrate; DPRQF-NH₂ (Dansyl); Peptide for Protease Assay
EINECS	Contact for details

Quality Control

Our Dansyl-Prolyl-Glutaminyl-Arginyl-Phenylalaninamide is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our production environment is designed to meet the rigorous demands of biochemical and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after each use to maintain integrity. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.