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Acetyl-Alanyl-Alanyl-Prolyl-(n-Methyl)Phenylalaninamide CAS NO 151657-05-5


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CAS No.:151657-05-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Acetyl-Alanyl-Alanyl-Prolyl-(n-Methyl)Phenylalaninamide is a synthetic peptide sequence of significant interest in advanced biochemical research and development. This compound serves as a critical building block and model substrate for studying protease specificity, enzyme kinetics, and peptide-based drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on metabolic pathways and therapeutic peptide design. The precise structure offers a valuable tool for investigating molecular interactions and developing novel bioactive compounds.

Application

  • Pharmaceutical Research & Development: As a specialized substrate for studying the activity and inhibition of specific proteolytic enzymes.
  • Biochemical Assay Development: Used in the design and validation of high-throughput screening assays for drug discovery programs.
  • Enzyme Kinetics Studies: Serves as a model peptide to determine kinetic parameters (Km, Vmax) and elucidate catalytic mechanisms of proteases.
  • Peptide Synthesis & Medicinal Chemistry: Acts as an intermediate or reference standard in the synthesis of more complex peptide analogs and potential therapeutic agents.
  • Academic & Institutional Research: Employed in university and institutional labs for fundamental research in biochemistry, molecular biology, and structural biology.
  • Quality Control Reference Standard: Can be utilized as a purity reference in analytical laboratories for method development and validation.

Basic Information

Product Name Acetyl-Alanyl-Alanyl-Prolyl-(n-Methyl)Phenylalaninamide
CAS No. 151657-05-5
Molecular Formula C26H38N6O6
Molecular Weight 530.62 g/mol
Synonyms Ac-AA-Pro-(N-Me)Phe-NH2; Acetyl-Ala-Ala-Pro-(N-Methyl)Phe-amide; N-Acetyl-L-alanyl-L-alanyl-L-prolyl-N-methyl-L-phenylalaninamide; AAPA(N-Me)F-NH2; Ac-Ala-Ala-Pro-(N-Me)Phe-NH2; Protease Substrate Peptide; N-Ac-AA-Pro-(N-Me)Phe-NH2; Ac-AA-P-(N-Me)F-NH2
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Quality Control

Our Acetyl-Alanyl-Alanyl-Prolyl-(n-Methyl)Phenylalaninamide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. We are committed to ISO 9001 quality management principles. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 95.0%
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 5.0%
Single Impurity (HPLC) ≤ 2.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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