Description

2-[(Dimethylamino)Methylene]Amino-3N-(Pivaloyloxy)Methyl-6-Methyl-5-Nitro-4-Pyrimidinol is a sophisticated pyrimidine derivative, a key synthetic intermediate in advanced organic synthesis. Its molecular architecture, featuring a nitro group and a pivaloyloxymethyl (POM) protecting group, makes it a critical building block for the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogs and antiviral or anticancer drug candidates.
• Agrochemical Research: Serves as a key building block for developing new pesticides and herbicides with specific modes of action.
• Chemical Synthesis: Used in academic and industrial R&D for constructing complex, functionalized pyrimidine scaffolds.
• Prodrug Development: The pivaloyloxymethyl (POM) group is a well-known prodrug moiety, making this compound valuable for designing bioreversible derivatives to enhance drug delivery.

Basic Information

Product Name	2-[(Dimethylamino)Methylene]Amino-3N-(Pivaloyloxy)Methyl-6-Methyl-5-Nitro-4-Pyrimidinol
CAS No.	151587-55-2
Molecular Formula	C14H21N5O5
Molecular Weight	339.35 g/mol
Synonyms	5-Nitro-6-methyl-4(3H)-pyrimidinone, 2-[[(dimethylamino)methylene]amino]-3-[(2,2-dimethyl-1-oxopropoxy)methyl]-; 2-((Dimethylamino)methyleneamino)-3-((pivaloyloxy)methyl)-6-methyl-5-nitropyrimidin-4(3H)-one; 2-[(Dimethylamino)methyleneamino]-3-(pivaloyloxymethyl)-6-methyl-5-nitro-4(3H)-pyrimidinone; POM-protected nitro pyrimidine intermediate; 2-Dimethylaminomethyleneamino-3-pivaloyloxymethyl-6-methyl-5-nitro-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 2-[(Dimethylamino)Methylene]Amino-3N-(Pivaloyloxy)Methyl-6-Methyl-5-Nitro-4-Pyrimidinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.