Description

Cyclo(Prolyl-Alanyl-Phenylalanyl-Leucyl) CAS NO 151545-20-9 is a synthetic cyclic tetrapeptide composed of the amino acids proline, alanine, phenylalanine, and leucine. This specific molecular architecture makes it a valuable scaffold in pharmaceutical research and development, particularly for studying peptide conformation and bioactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic peptides.
• Medicinal Chemistry: Used as a molecular scaffold to explore structure-activity relationships (SAR) and develop new drug candidates.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor binding, and other biological interactions due to its constrained cyclic structure.
• Academic Research: A valuable tool in university and institutional labs for teaching and investigating peptide chemistry and conformational analysis.
• Reference Standard: Used in analytical laboratories for method development and quality control of related peptide substances.

Basic Information

Product Name	Cyclo(Prolyl-Alanyl-Phenylalanyl-Leucyl)
CAS No.	151545-20-9
Molecular Formula	C26H36N4O5
Molecular Weight	484.59 g/mol
Synonyms	Cyclo(Pro-Ala-Phe-Leu); c(P-A-F-L); Cyclo(L-Prolyl-L-alanyl-L-phenylalanyl-L-leucyl); Cyclic Tetrapeptide P-A-F-L; Cyclo(Pro-Ala-Phe-Leu) Tetrapeptide; 151545-20-9; Cyclo(Pro-Ala-Phe-Leu) cyclic peptide
EINECS	Contact for details

Quality Control

Our Cyclo(Prolyl-Alanyl-Phenylalanyl-Leucyl) is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.