Description

8-[(E)-2-(4-Methoxy-2,5-Dimethyl-Phenyl)Ethenyl]-7-Methyl-1,3-Dipropyl -Purine-2,6-Dione is a high-purity, synthetic purine derivative designed for advanced research and development applications. This compound serves as a critical intermediate in the synthesis of novel pharmaceutical candidates, particularly those targeting adenosine receptor pathways. It is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel adenosine receptor antagonists and other purine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Serves as a reference standard or ligand in enzymatic and receptor-binding assays.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-[(E)-2-(4-Methoxy-2,5-Dimethyl-Phenyl)Ethenyl]-7-Methyl-1,3-Dipropyl -Purine-2,6-Dione
CAS No.	151539-39-8
Molecular Formula	C23H28N4O3
Molecular Weight	408.50 g/mol
Synonyms	8-[(E)-2-(4-Methoxy-2,5-dimethylphenyl)ethenyl]-7-methyl-1,3-dipropylpurine-2,6-dione; 1,3-Dipropyl-8-[(E)-2-(4-methoxy-2,5-dimethylphenyl)ethenyl]-7-methylxanthine; 8-(4-Methoxy-2,5-dimethylstyryl)-7-methyl-1,3-dipropylxanthine; KW-6002 (common research code); Istradefylline Impurity/Intermediate; Adenosine A2A Receptor Antagonist Intermediate; (E)-8-(3,4-Dimethyl-6-methoxystyryl)-7-methyl-1,3-dipropylxanthine
EINECS	Contact for details

Quality Control

Our 8-[(E)-2-(4-Methoxy-2,5-Dimethyl-Phenyl)Ethenyl]-7-Methyl-1,3-Dipropyl -Purine-2,6-Dione is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.