Description

77-Kd Merozoite Protein, Babesia CAS NO 151472-22-9 is a highly purified, recombinant protein antigen derived from the merozoite stage of Babesia parasites. This critical reagent is essential for the research and development of advanced diagnostic assays and vaccine candidates targeting babesiosis, a significant tick-borne disease affecting livestock and, increasingly, humans. It is primarily utilized by biotechnology firms, veterinary pharmaceutical developers, and academic research institutions focused on parasitology and immunology.

Application

• Diagnostic Kit Development: Serves as a key capture or detection antigen in ELISA, lateral flow, and other immunoassays for the specific and sensitive detection of Babesia infections.
• Vaccine Research: Used as an immunogen in preclinical studies to evaluate protective immune responses and as a candidate antigen for subunit vaccine formulation.
• Antibody Production & Purification: Employed to immunize hosts for generating polyclonal or monoclonal antibodies, and as an affinity ligand for purifying specific antibodies from serum.
• Serological Studies: Facilitates epidemiological surveys and seroprevalence studies to understand the spread and impact of babesiosis in various host populations.
• Host-Pathogen Interaction Research: A vital tool for investigating the mechanisms of erythrocyte invasion by Babesia merozoites and the subsequent host immune response.
• Quality Control Reference: Acts as a positive control and calibration standard in the manufacturing and validation of commercial diagnostic tests.

Basic Information

Product Name	77-Kd Merozoite Protein, Babesia
CAS No.	151472-22-9
Molecular Formula	Contact for details
Molecular Weight	~77 kDa (Theoretical)
Synonyms	Babesia Merozoite Surface Antigen; 77 kDa Merozoite Antigen; BmSA; Recombinant Babesia Protein; P77; Babesia bovis Merozoite Surface Protein; Babesiosis Diagnostic Antigen; Veterinary Diagnostic Reagent
EINECS	Contact for details

Quality Control

Our recombinant 77-Kd Merozoite Protein is manufactured under stringent quality systems to ensure batch-to-batch consistency and high biological activity. Each lot is subjected to comprehensive analytical testing, including SDS-PAGE, Western Blot, and endotoxin level assessment. A Certificate of Analysis (COA) detailing purity, identity, and functional activity is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (Western Blot)	Reacts with specific anti-Babesia antisera
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in PBS or appropriate aqueous buffer
Biological Activity (ELISA)	Binds specifically to relevant monoclonal antibodies

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.