Description

Z-D-Ala-Nh2 is a protected D-alanine derivative, specifically the benzyloxycarbonyl (Z) amide of D-alanine. This chiral building block is essential for the controlled synthesis of peptides and peptidomimetics, ensuring the correct stereochemistry is maintained during complex chemical reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic probes, and advanced biomaterials.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-alanine residues with orthogonal protection.
• Biochemical Research: Serves as a precursor for studying enzyme specificity, receptor-ligand interactions, and metabolic pathways involving D-amino acids.
• Proteomics & Diagnostics: Employed in the design and synthesis of specialized peptide sequences for diagnostic assays and biomarker discovery.
• Material Science: A building block for creating synthetic polymers and biomimetic materials with specific chiral properties.

Basic Information

Product Name	Z-D-Ala-Nh2
CAS No.	151378-81-3
Molecular Formula	C11H14N2O3
Molecular Weight	222.24 g/mol
Synonyms	N-(Benzyloxycarbonyl)-D-alaninamide; D-Alaninamide, N-[(phenylmethoxy)carbonyl]-; Z-D-Alanine amide; (R)-2-((Benzyloxycarbonyl)amino)propanamide; N-Cbz-D-alaninamide; CBZ-D-Ala-NH2; Nα-Carbobenzoxy-D-alaninamide; N-[(Benzyloxy)carbonyl]-D-alaninamide
EINECS	Contact for details

Quality Control

Our Z-D-Ala-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.