Description

Pyroglutamylglutamine Diketopiperazine is a specialized cyclic dipeptide derivative formed from pyroglutamic acid and glutamine. This compound is of significant interest in advanced biochemical research and high-value synthesis due to its unique structural motif, which is a key scaffold in peptide chemistry and medicinal research. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries, particularly in the development of bioactive peptides and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Cosmetic Actives: Investigated for potential use in anti-aging and skin-repair formulations due to its peptide structure, which may influence collagen synthesis and skin barrier function.
• Nutraceutical Development: Explored as a potential bioactive component in functional foods and dietary supplements targeting cellular health and protein metabolism.
• Chemical Synthesis: Acts as a chiral template or precursor in the asymmetric synthesis of more complex organic molecules and natural product analogs.

Basic Information

Product Name	Pyroglutamylglutamine Diketopiperazine
CAS No.	151367-91-8
Molecular Formula	C10H14N4O5
Molecular Weight	270.24 g/mol
Synonyms	Cyclo(pGlu-Gln); 2,5-Diketopiperazine-1-acetyl-6-(5-oxopyrrolidine-2-carboxamide); L-Pyroglutamyl-L-glutamine 2,5-diketopiperazine; Pyrrolidonylglutamine DKP; pGlu-Gln DKP; (3S,6S)-3-(2-Amino-2-oxoethyl)-6-(5-oxopyrrolidine-2-carbonyl)piperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Pyroglutamylglutamine Diketopiperazine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.