Description

Antarelix is a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH) with potent antagonistic activity. This compound is a critical research tool and pharmaceutical intermediate used to study and modulate hormonal pathways. It is primarily utilized by pharmaceutical R&D departments, biotechnology firms, and academic research institutions. The product is supplied as a high-purity material to ensure reliable and reproducible results in advanced therapeutic development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the development of novel GnRH antagonist therapies.
• Endocrinology Studies: Used in preclinical and clinical research to investigate the regulation of gonadotropin secretion and sex hormone-dependent conditions.
• Oncology Research: Explored in studies targeting hormone-sensitive cancers, such as prostate and breast cancer, due to its ability to suppress sex hormone production.
• Reproductive Medicine: Applied in research related to fertility control, assisted reproduction technologies, and the treatment of disorders like endometriosis.
• Biochemical Assay Development: Functions as a precise ligand in receptor binding assays and other in vitro diagnostic tests.
• Peptide Chemistry & Synthesis: Used as a building block or model compound for advanced peptide synthesis and structural analysis.

Basic Information

Product Name	Antarelix
CAS No.	151272-78-5
Molecular Formula	C₆₀H₈₆N₁₈O₁₂
Molecular Weight	1243.5 g/mol
Synonyms	Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-Tyr-D-Hci-Leu-Lys(iPr)-Pro-D-Ala-NH₂; [Ac-D-2Nal¹, D-4Cpa², D-3Pal³, Arg⁵, D-Hci⁶, Leu⁷, Lys(iPr)⁸, D-Ala¹⁰]GnRH; Antarelix Acetate; GnRH Antagonist (Antarelix); EP 24332
EINECS	Contact for details

Quality Control

Our Antarelix is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	5.0% - 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.