Description

β-Amyloid (32-35) is a synthetic peptide fragment corresponding to residues 32-35 of the human amyloid-beta protein. This specific sequence is of significant interest in neuroscience and Alzheimer's disease research for studying molecular interactions, aggregation mechanisms, and potential therapeutic targets. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neurodegenerative disease studies and diagnostic development.

Application

• Biochemical Research: Used as a critical reference standard and tool peptide in Alzheimer's disease pathology studies.
• Drug Discovery: Screening and validation of compounds designed to inhibit amyloid-beta aggregation or toxicity.
• Antibody Development: Serves as an antigen for the production and characterization of site-specific antibodies.
• Diagnostic Assays: Employed in the development and calibration of ELISA, Western blot, and other immunoassays targeting amyloid-beta epitopes.
• Structure-Activity Relationship (SAR) Studies: Investigating the role of specific amino acid residues in amyloid-beta peptide aggregation and neurotoxicity.
• Academic Research: Fundamental studies on protein misfolding, peptide self-assembly, and neurodegenerative mechanisms.

Basic Information

Item	Detail
Product Name	β-Amyloid (32-35)
CAS No.	151151-30-3
Molecular Formula	C20H34N6O7
Molecular Weight	470.52 g/mol
Synonyms	Amyloid β-Protein (32-35); Aβ (32-35); Amyloid β-Peptide (32-35); H-Ile-Ile-Gly-Leu-OH; IIGL; CAS 151151-30-3; Aβ32-35; β-Amyloid Peptide (32-35)
EINECS	Contact for details

Quality Control

Our β-Amyloid (32-35) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, essential for reliable research outcomes. Quality is verified through comprehensive analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Net Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in DMSO, DMF; partly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.