Description

Dnp-Pro-β-Cyclohexyl-Ala-Abu-Cys(Me)-His-Ala-Lys(n-Me-Abz)-Nh2 is a complex, custom synthetic peptide featuring a dinitrophenyl (Dnp) protecting group and a modified lysine residue with a methylated aminobenzoic acid (n-Me-Abz) side chain. This compound is primarily utilized as a critical research-grade biochemical tool for studying enzyme kinetics, receptor-ligand interactions, and signal transduction pathways. It is essential for pharmaceutical R&D, academic research, and biotechnology applications focused on protease specificity, peptide-based drug discovery, and advanced biochemical assays.

Application

• Protease & Enzyme Substrate Research: Serves as a specialized fluorogenic or chromogenic substrate for investigating the activity and inhibition of specific proteases.
• Drug Discovery & Medicinal Chemistry: Used in high-throughput screening (HTS) assays to identify and characterize novel peptide-based therapeutic candidates and enzyme inhibitors.
• Biochemical Mechanism Studies: A key reagent for elucidating catalytic mechanisms, binding affinities, and structure-activity relationships (SAR) in biochemical pathways.
• Custom Peptide Synthesis Reference: Acts as a benchmark or intermediate in the synthesis of complex, modified peptides for advanced research applications.
• Diagnostic Assay Development: Employed in the development of sensitive and specific diagnostic assays for detecting enzymatic activity relevant to disease states.

Basic Information

Product Name	Dnp-Pro-β-Cyclohexyl-Ala-Abu-Cys(Me)-His-Ala-Lys(n-Me-Abz)-Nh2
CAS No.	150956-93-7
Molecular Formula	C52H76N14O12S
Molecular Weight	1121.3 g/mol
Synonyms	Dnp-Pro-β-Cyclohexyl-Ala-Abu-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2; N-2,4-Dinitrophenyl-Prolyl-β-Cyclohexylalanyl-Alanyl-α-Aminobutyryl-S-Methylcysteinyl-Histidyl-Alanyl-Nε-Methyl-Nε-(4-aminobenzoyl)-Lysinamide; Custom Peptide 150956-93-7; Fluorogenic Peptide Substrate; Dnp-protected Peptide; Modified Lysine Peptide; Protease Research Peptide
EINECS	Contact for details

Quality Control

Every batch of this research peptide is manufactured under strict quality control protocols. Purity and identity are confirmed via advanced analytical techniques including HPLC and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing purity, molecular weight verification, and chromatographic data to ensure consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.