Description

Ofloxacin Pivaloyloxymethyl Ester is a key pharmaceutical intermediate, specifically a prodrug ester of the broad-spectrum fluoroquinolone antibiotic ofloxacin. This compound is designed to enhance the bioavailability and pharmacokinetic profile of the active parent drug, making it a critical component in advanced pharmaceutical manufacturing. It is primarily utilized by fine chemical and active pharmaceutical ingredient (API) producers for the development and synthesis of high-potency antibiotic formulations.

Application

• Pharmaceutical Intermediate: Primary use as a prodrug in the synthesis of advanced ofloxacin-based antibiotic formulations.
• API Manufacturing: A critical raw material in the production chain for active pharmaceutical ingredients (APIs) belonging to the fluoroquinolone class.
• Drug Delivery Optimization: Employed in research and development to improve drug solubility, stability, and absorption rates.
• Veterinary Medicine: Used in the development of antibiotic treatments for bacterial infections in animals.
• Clinical Research: Serves as a reference standard and building block in pharmacological studies and new drug entity development.

Basic Information

Product Name	Ofloxacin Pivaloyloxymethyl Ester
CAS No.	150871-00-4
Molecular Formula	C24H29FN2O6
Molecular Weight	460.50 g/mol
Synonyms	Ofloxacin Pivalate Ester; Ofloxacin Pivaloyloxymethyl Ester; Ofloxacin POM Ester; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, (pivaloyloxy)methyl ester; Ofloxacin Pivaloyloxymethyl; Ofloxacine Pivaloyloxymethylester; Ofloxacine Pivalate; Ofloxacin Pivaloyloxymethyl Ester (POM)
EINECS	Contact for details

Quality Control

Our Ofloxacin Pivaloyloxymethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, and we can support compliance with cGMP, ICH guidelines, and relevant pharmacopoeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.