Description

5-Hydroxy-α-Methyl-L-Tryptophan is a specialized, non-proteinogenic amino acid derivative that serves as a key chiral building block and biochemical intermediate. This compound is valued for its role in the research and development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those with neurological or psychiatric applications.
• Biochemical Research: Used as a standard or reagent in studies involving serotonin biosynthesis, metabolism, and related enzymatic pathways.
• Chiral Synthesis: Employed as a building block for constructing complex, stereochemically defined molecules in medicinal chemistry.
• Metabolite Analysis: Serves as a reference compound in analytical methods (HPLC, LC-MS) for detecting and quantifying related metabolites in biological samples.
• Enzyme Inhibition Studies: Investigated for its potential as an inhibitor or modulator in studies of tryptophan hydroxylase and related enzymes.

Basic Information

Product Name	5-Hydroxy-α-Methyl-L-Tryptophan
CAS No.	150852-19-0
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	α-Methyl-5-hydroxy-L-tryptophan; (2S)-2-Amino-2-methyl-3-(5-hydroxy-1H-indol-3-yl)propanoic acid; 5-Hydroxy-α-methyl-L-tryptophan; 5-Hydroxy-α-methyltryptophan; L-α-Methyl-5-hydroxytryptophan; 5-Hydroxy-α-methyltryptophan (L-form); 150852-19-0; α-Methyl-5-hydroxy-L-tryptophan
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-α-Methyl-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.