Description

1-(1,1-Dimethylethyl)-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules. It is primarily sought by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions engaged in antimicrobial development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of next-generation fluoroquinolone antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for new antibiotic candidates.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Biochemical Research: Employed as a reference standard or inhibitor in studies targeting bacterial DNA gyrase and topoisomerase IV.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing of specialized quinolone derivatives.

Basic Information

Product Name	1-(1,1-Dimethylethyl)-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	150805-04-2
Molecular Formula	C₁₄H₁₂F₃NO₃
Molecular Weight	299.25 g/mol
Synonyms	6,7,8-Trifluoro-1-(tert-butyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; 1-tert-Butyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; tert-Butyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6,7,8-Trifluoro-1-(1,1-dimethylethyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 150805-04-2; TFQ carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 1-(1,1-Dimethylethyl)-6,7,8-Trifluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.