Description

tert-Butyloxycarbonylalanyl-Dehydrophenylalanyl-(n-Methyl)Dehydrophenylalaninamide is a specialized peptide derivative featuring a dehydrophenylalanine residue and an N-methylated dehydrophenylalanine amide, protected by a Boc (tert-butyloxycarbonyl) group. This compound is a critical building block in advanced peptide synthesis, enabling the introduction of constrained, non-natural amino acid motifs that enhance the metabolic stability and receptor selectivity of therapeutic peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based drugs, hormone analogs, and diagnostic agents targeting complex biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for novel peptide therapeutics and hormone analogs.
• Peptide Drug Discovery: Used in solid-phase and solution-phase peptide synthesis to incorporate conformationally constrained amino acids.
• Biochemical Research: Employed in structure-activity relationship (SAR) studies to investigate peptide-protein interactions.
• Protease Inhibitor Development: Acts as a core scaffold for designing inhibitors that mimic transition states.
• Labeled Peptide Synthesis: A starting material for creating peptides tagged with fluorescent or radioactive markers for diagnostic imaging.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	tert-Butyloxycarbonylalanyl-Dehydrophenylalanyl-(n-Methyl)Dehydrophenylalaninamide
CAS No.	150529-59-2
Molecular Formula	C29H34N4O5
Molecular Weight	518.61 g/mol
Synonyms	Boc-Ala-δPhe-N-Me-δPhe-NH2; Boc-L-Alanyl-dehydro-L-phenylalanyl-N-methyl-dehydro-L-phenylalaninamide; N-(tert-Butoxycarbonyl)alanyl-α,β-dehydrophenylalanyl-N-methyl-α,β-dehydrophenylalaninamide; Boc-Ala-(Z)-Phe-N-Me-(Z)-Phe-NH2; (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)propanamido)-3-phenylacryloyl-N-methyl-3-phenylacrylamide; Peptide Building Block 150529-59-2; Dehydroamino Acid Peptide Derivative
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonylalanyl-Dehydrophenylalanyl-(n-Methyl)Dehydrophenylalaninamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular mass
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.