Description

Fibronectin Fragment (196-203) is a synthetic peptide fragment derived from the cell-binding domain of human fibronectin. This bioactive sequence plays a critical role in mediating cell adhesion and signaling through integrin receptor interactions. It is an essential research tool for scientists in cell biology, oncology, and tissue engineering, enabling studies on cellular migration, angiogenesis, and extracellular matrix dynamics.

Application

• Biomedical Research: Used as a key reagent in studies investigating cell adhesion, migration, and integrin-mediated signaling pathways.
• Cancer Research: Employed to explore the role of fibronectin fragments in tumor metastasis, angiogenesis, and cancer cell proliferation.
• Tissue Engineering & Regenerative Medicine: Serves as a bioactive coating or component in scaffolds to promote cell attachment and growth for in vitro and in vivo applications.
• Drug Discovery & Screening: Utilized in assays to identify and evaluate potential therapeutic compounds that modulate integrin-fibronectin interactions.
• Biomaterial Development: Incorporated into surface modifications of implants and medical devices to enhance biocompatibility and host tissue integration.

Basic Information

Product Name	Fibronectin Fragment (196-203)
CAS No.	150525-72-7
Molecular Formula	C41H62N12O11
Molecular Weight	899.01 g/mol
Synonyms	Fibronectin Cell-Adhesion Peptide; Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro; RGDSPASSKP; Fibronectin (196-203); FN (196-203); GRGDSP; Fibronectin Adhesion-Promoting Peptide; GRGDSPASSKP
EINECS	Contact for details

Quality Control

Our Fibronectin Fragment (196-203) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and MS for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.