Description

Fibronectin Cs-1 Fragment (1978-1982) is a specific, biologically active peptide sequence derived from the cell-binding domain of human fibronectin. This fragment is critical for research and development in cell adhesion studies, as it mimics the key interaction site for integrin receptors. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in biomaterial engineering, cell culture optimization, and therapeutic discovery.

Application

• Cell Adhesion & Migration Research: Used as a coating substrate to study integrin-mediated cell attachment, spreading, and motility in vitro.
• Biomaterial Functionalization: Immobilized on surfaces of medical devices, scaffolds, and implants to enhance biocompatibility and promote specific cellular integration.
• Diagnostic Assay Development: Serves as a capture ligand in assays designed to detect or quantify specific integrin expression or activity.
• Drug Discovery Screening: Employed in high-throughput screening platforms to identify novel compounds that modulate the fibronectin-integrin interaction pathway.
• Stem Cell Culture: Applied to culture surfaces to improve the attachment, growth, and maintenance of pluripotency in various stem cell lines.
• Angiogenesis Studies: Investigated for its role in endothelial cell behavior and blood vessel formation models.

Basic Information

Product Name	Fibronectin Cs-1 Fragment (1978-1982)
CAS No.	150525-67-0
Molecular Formula	C106H174N32O33S2
Molecular Weight	~2392.8 g/mol
Synonyms	Fibronectin Cell Attachment Peptide; CS1 Peptide; FN CS1 Fragment; Arg-Gly-Asp-Ser (RGDS) containing peptide; LDV Peptide; Connecting Segment-1 Peptide; FNIII9-10 CS1 Region; V region peptide; H-Gly-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-His-Pro-Asn-Tyr-His-Ile-Gly-Ser-Arg-Asn-Ala-Tyr-Glu-Thr-Ile-Trp-Ser-Pro-Arg-Ser-Leu-Asn-Asp-Lys-Thr-Tyr-Arg-Gly-Asp-Ser-OH
EINECS	Contact for details

Quality Control

Our Fibronectin Cs-1 Fragment is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive biological applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity. We adhere to ISO 9001 quality management principles, and our processes are designed to support research requiring reliable and reproducible performance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 8.0%
Biological Activity (Cell Adhesion)	Active

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.