Description

L-N5-(1-Iminopropyl) Ornithine (Hydrochloride) is a high-purity, chemically defined derivative of the amino acid ornithine, widely recognized for its role as a potent and selective inhibitor of nitric oxide synthase (NOS). This compound is critical for researchers and manufacturers requiring precise biochemical tools to study and modulate the nitric oxide pathway. It is primarily utilized in pharmaceutical R&D, academic research, and the production of advanced intermediates for therapeutic agents targeting cardiovascular and inflammatory conditions.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying the role of nitric oxide synthase (NOS) in various disease models, including cardiovascular disorders, inflammation, and neurological conditions.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of novel therapeutic compounds designed to modulate the NO pathway.
• Biochemical Assay Standard: Used as a reference standard in enzymatic assays to quantify NOS activity and screen for potential inhibitors in drug discovery pipelines.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research into cell signaling, vascular biology, and immune response mechanisms.
• Preclinical Studies: Utilized in animal model studies to investigate the therapeutic potential of NOS inhibition for specific medical applications.

Basic Information

Product Name	L-N5-(1-Iminopropyl) Ornithine (Hydrochloride)
CAS No.	150403-96-6
Molecular Formula	C8H18N3O2 • HCl
Molecular Weight	233.71 g/mol
Synonyms	L-NIO Hydrochloride; N5-(1-Imino-3-butenyl)-L-ornithine Hydrochloride; L-N5-(1-Iminopropyl)ornithine HCl; (S)-2,5-Diamino-N-(1-iminopropyl)pentanamide Hydrochloride; Nω-Iminopropyl-L-ornithine Hydrochloride; L-Ornithine, N5-(1-iminopropyl)-, hydrochloride; N5-(1-Iminopropyl)-L-ornithine hydrochloride; Nitric Oxide Synthase Inhibitor I
EINECS	Contact for details

Quality Control

Our L-N5-(1-Iminopropyl) Ornithine (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.