Description

L-N6-(1-Iminoethyl)Lysine Dihydrochloride is a high-purity, chemically defined derivative of the amino acid lysine, widely recognized as a potent and selective inhibitor of inducible nitric oxide synthase (iNOS). This compound is essential for biochemical research and pharmaceutical development, enabling the study of nitric oxide signaling pathways and their roles in inflammation and disease. It is a critical reagent for researchers and manufacturers in the fields of pharmacology, immunology, and molecular biology, as well as for companies developing novel therapeutic agents.

Application

• Biochemical Research: A key tool for selectively inhibiting iNOS activity in cell culture and in vitro enzymatic assays to study the role of nitric oxide in cellular signaling and pathophysiology.
• Pharmaceutical R&D: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of anti-inflammatory and immunomodulatory drugs.
• Academic Research: Employed in university and institutional labs for investigating conditions like septic shock, neurodegenerative diseases, and autoimmune disorders where iNOS is implicated.
• Diagnostic Development: Serves as a critical component in the development of diagnostic kits and assays designed to measure iNOS activity or screen for iNOS inhibitors.
• Preclinical Studies: Utilized in animal model studies to validate the therapeutic potential of iNOS inhibition for various inflammatory conditions.

Basic Information

Product Name	L-N6-(1-Iminoethyl)Lysine Dihydrochloride
CAS No.	150403-89-7
Molecular Formula	C8H19Cl2N3O2
Molecular Weight	260.16 g/mol
Synonyms	L-NIL dihydrochloride; N6-(1-Iminoethyl)-L-lysine dihydrochloride; L-N6-(1-Iminoethyl)lysine dihydrochloride; iNOS Inhibitor II; NIL; (2S)-2,6-Diamino-2-(1-iminoethylamino)hexanoic acid dihydrochloride; L-N6-(1-Iminoethyl)lysine HCl; 150403-89-7
EINECS	Contact for details

Quality Control

Our L-N6-(1-Iminoethyl)Lysine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for pharmaceutical intermediates and biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.