Description

n-9-Fluorenylmethoxycarbonyl-Se-4-Methoxybenzylselenocysteine is a specialized, protected selenocysteine derivative designed for advanced peptide synthesis and biochemical research. This compound is critical for the site-specific incorporation of selenocysteine, enabling the study of protein structure, function, and redox activity. It is an essential building block for researchers and manufacturers in pharmaceutical development, proteomics, and the production of selenoproteins, where precise control over amino acid sequence and post-translational modifications is required.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, facilitating the controlled introduction of selenocysteine into peptide chains.
• Selenoprotein Research & Production: Enables the biosynthesis and study of selenoproteins, which are crucial for antioxidant defense and thyroid hormone metabolism.
• Pharmaceutical Intermediate: Serves as a critical precursor in the development of novel therapeutic peptides and biologics targeting oxidative stress pathways.
• Bioconjugation & Chemical Biology: Used to create selenol-containing probes for labeling, structural analysis (e.g., phasing in X-ray crystallography), and studying enzyme mechanisms.
• Antioxidant Peptide Development: Incorporated into synthetic peptides designed to mimic or enhance natural glutathione peroxidase activity.

Basic Information

Item	Detail
Product Name	n-9-Fluorenylmethoxycarbonyl-Se-4-Methoxybenzylselenocysteine
CAS No.	150308-80-8
Molecular Formula	C26H23NO5Se
Molecular Weight	500.43 g/mol
Synonyms	Fmoc-Sec(Mob)-OH; Fmoc-Selenocysteine(4-Methoxybenzyl)-OH; N-α-Fmoc-Se-(4-methoxybenzyl)-L-selenocysteine; (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(4-methoxyphenyl)methylselanyl]propanoic acid; Se-(4-Methoxybenzyl)-N-Fmoc-L-selenocysteine; Fmoc-L-Sec(Mob)-OH; Protected Selenocysteine Derivative; Selenocysteine Building Block
EINECS	Contact for details

Quality Control

Our n-9-Fluorenylmethoxycarbonyl-Se-4-Methoxybenzylselenocysteine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and cGMP-guided applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house specifications to meet the demands of pharmaceutical R&D and advanced peptide synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.