Description

H-Dl-Isoser-Phe-Leu-Leu-Arg-Asn-Oh is a synthetic peptide derivative, specifically a heptapeptide amide containing the non-proteinogenic amino acid isoserine. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the design of novel therapeutic agents and biochemical probes. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and proteomics. The product is supplied to meet the stringent requirements of R&D laboratories and production facilities focused on peptide-based drug discovery.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of complex peptide-based drug candidates targeting various disease pathways.
• Medicinal Chemistry: Serves as a building block or a reference compound for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Proteomics & Peptide Mapping: Acts as a standard or a model peptide in mass spectrometry and chromatographic analysis for method development and validation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry, molecular biology, and signal transduction.
• Contract Manufacturing (CMO): Supplied as a high-purity raw material for the cGMP production of active pharmaceutical ingredients (APIs) for clinical trials.

Basic Information

Product Name	H-Dl-Isoser-Phe-Leu-Leu-Arg-Asn-Oh
CAS No.	150242-29-8
Molecular Formula	C41H68N12O10
Molecular Weight	865.05 g/mol
Synonyms	H-DL-Isoser-Phe-Leu-Leu-Arg-Asn-OH; DL-Isoser-Phe-Leu-Leu-Arg-Asn-OH; Heptapeptide H-DL-Isoser-Phe-Leu-Leu-Arg-Asn-OH; Argireline Fragment; Acetyl Hexapeptide-8 Related Peptide; 150242-29-8; H-DL-Isoleucyl-phenylalanyl-leucyl-leucyl-arginyl-asparagine; N-[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-Amino-1-[[(1S)-1-carbamoylethyl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-phenyl-1-oxopropan-2-yl]-2-hydroxypropanamide
EINECS	Contact for details

Quality Control

Our H-Dl-Isoser-Phe-Leu-Leu-Arg-Asn-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that include data from HPLC, MS, and NMR. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, supporting both research and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.