Description

n-Formylmethionyl-Prolyl-Phenylalanine Methyl Ester is a synthetic tripeptide derivative, specifically a formylated methionine-proline-phenylalanine sequence with a C-terminal methyl ester. This compound serves as a crucial advanced pharmaceutical intermediate and a valuable building block in peptide synthesis and medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents, enzyme inhibitors, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop enzyme inhibitors or receptor modulators.
• Biochemical Tool Compound: Serves as a substrate or inhibitor in enzymatic assays and proteomics research.
• Peptide Synthesis: An important fragment for solid-phase or solution-phase peptide synthesis (SPPS) to construct longer peptide chains.
• Academic & Institutional Research: Utilized in universities and research institutes for studying peptide stability, metabolism, and biological activity.

Basic Information

Product Name	n-Formylmethionyl-Prolyl-Phenylalanine Methyl Ester
CAS No.	150178-44-2
Molecular Formula	C21H29N3O5S
Molecular Weight	435.54 g/mol
Synonyms	N-Formyl-Met-Pro-Phe-OMe; F-Met-Pro-Phe-OMe; N-Formylmethionylprolylphenylalanine Methyl Ester; Formyl-Met-Pro-Phe Methyl Ester; Formylmethionylprolylphenylalanine Methyl Ester; L-Phenylalanine, N-formyl-L-methionyl-L-prolyl-, methyl ester; Methyl N-formyl-L-methionyl-L-prolyl-L-phenylalaninate
EINECS	Contact for details

Quality Control

Our n-Formylmethionyl-Prolyl-Phenylalanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.