Description

2-Amino-4-Oxo-5-Phosphonopentanoic Acid is a specialized phosphonic acid derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a potent and selective antagonist for specific glutamate receptor subtypes, making it a critical tool for neurobiological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on neuroscience and metabolic pathway investigation.

Application

• Neuroscience Research: As a selective NMDA receptor antagonist for studying excitatory neurotransmission, synaptic plasticity, and neurological disorders.
• Pharmaceutical Intermediate: Used in the synthesis and development of novel neuroprotective agents or central nervous system (CNS) targeted drugs.
• Biochemical Tool Compound: Employed in enzyme inhibition studies, particularly those involving glutamate-metabolizing enzymes or phosphate transfer.
• Metabolic Pathway Analysis: Investigates the role of glutamate analogs in cellular metabolism and signaling cascades.
• Reference Standard: Serves as a high-purity analytical standard for quality control in related pharmaceutical manufacturing.

Basic Information

Product Name	2-Amino-4-Oxo-5-Phosphonopentanoic Acid
CAS No.	150039-21-7
Molecular Formula	C5H10NO7P
Molecular Weight	227.11 g/mol
Synonyms	AP5; 2-Amino-5-phosphonopentanoic acid, 4-oxo-; 5-Phosphono-DL-norvaline, 4-oxo-; (RS)-2-Amino-4-oxo-5-phosphonopentanoic acid; DL-AP5, 4-oxo-; Glutamate phosphonate analog; NMDA receptor antagonist AP5 variant; 4-Oxo-AP5
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Oxo-5-Phosphonopentanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.