Description

2-Bromo-5-Methylpyrimidine is a versatile halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters because it serves as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling critical carbon-carbon and carbon-heteroatom bond formations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate for Suzuki, Stille, and Negishi cross-coupling reactions to introduce the pyrimidine moiety.
• Nucleophilic Substitution: The bromine atom is readily displaced in reactions with various nucleophiles, enabling diverse functionalization.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biological target validation.

Basic Information

Product Name	2-Bromo-5-Methylpyrimidine
CAS No.	150010-20-1
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	5-Methyl-2-bromopyrimidine; 2-Bromo-5-methylpyrimidine; 5-Methylpyrimidine, 2-bromo-; Bromo-5-methylpyrimidine; 2-Bromo-5-methyl-pyrimidine; 150010-20-1; SCHEMBL11841527; DTXSID90672966
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methylpyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.